We are happy to share our new paper in Cell Reports, where we introduce membrane mucin MUC17 as new component of the mutilfaceted intestinal barrier. Elena has led this project, which revealed that MUC17 is associated with an innate immunity repertoire is triggered in the small intestine during the weaning transition. At this crucial event in mammalian development, MUC17 expression is induced in enterocytes, upon which MUC17 localizes to the brush border membrane to function as a barrier that prevents bacteria from binding to the host epithelium.
Congratulations, Elena, and thank you to all lab members and colleagues in the Mucin Biology Groups at University of Gothenburg!